{"id":20498,"date":"2024-11-10T15:35:00","date_gmt":"2024-11-10T13:35:00","guid":{"rendered":"https:\/\/physiomed.store\/inflammaging-%cf%86%ce%bb%ce%b5%ce%b3%ce%bc%ce%bf%ce%bd%ce%ae-%ce%b3%ce%ae%cf%81%ce%b1%ce%bd%cf%83%ce%b7-2\/"},"modified":"2024-11-10T15:35:00","modified_gmt":"2024-11-10T13:35:00","slug":"inflammaging-%cf%86%ce%bb%ce%b5%ce%b3%ce%bc%ce%bf%ce%bd%ce%ae-%ce%b3%ce%ae%cf%81%ce%b1%ce%bd%cf%83%ce%b7-2","status":"publish","type":"post","link":"https:\/\/physiomed.store\/en\/inflammaging-%cf%86%ce%bb%ce%b5%ce%b3%ce%bc%ce%bf%ce%bd%ce%ae-%ce%b3%ce%ae%cf%81%ce%b1%ce%bd%cf%83%ce%b7-2\/","title":{"rendered":"Inflammaging: \u03a6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae + \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7"},"content":{"rendered":"<p>&nbsp;<\/p>\n<div><a href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEiiDwdjtpPWckr5ZDobC1eo5If9nDJwefk1QLhl3qBVS-sVlVZfQlza8DkXlE8x5Txp9wv6BDZefLLwJgazqK-VSScf_J6C612bRXSEpBQb7By2-h9aC1NvoRI1cDTEI57k1MKvXrg59S46rnizTlk2zf7bdxCyQEadUTVSGMeE3hCpyGF1jxtrOIPXius\/s1748\/41392_2023_1502_Fig1_HTML.webp\"><img fetchpriority=\"high\" decoding=\"async\" border=\"0\" height=\"390\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEiiDwdjtpPWckr5ZDobC1eo5If9nDJwefk1QLhl3qBVS-sVlVZfQlza8DkXlE8x5Txp9wv6BDZefLLwJgazqK-VSScf_J6C612bRXSEpBQb7By2-h9aC1NvoRI1cDTEI57k1MKvXrg59S46rnizTlk2zf7bdxCyQEadUTVSGMeE3hCpyGF1jxtrOIPXius\/w640-h390\/41392_2023_1502_Fig1_HTML.webp\" width=\"640\" \/><\/a><\/div>\n<p>\u0397 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 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\u03c6\u03b1\u03b9\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 (SASP)*, \u03c0\u03c1\u03bf\u03ac\u03b3\u03bf\u03c5\u03bd \u03c4\u03b7 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03bf\u03c5\u03bd \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 \u03c3\u03b5 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1. <\/p>\n<p><a name=\"more\"><\/a>\u03a4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1, \u03b7 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03b5\u03c0\u03b9\u03c4\u03b1\u03c7\u03cd\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 \u03c4\u03c9\u03bd 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\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7\u03c2, \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b5\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03be\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c4\u03b5\u03c5\u03b8\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b7\u03bd \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7, \u03c0\u03b1\u03c1\u03ad\u03c7\u03bf\u03bd\u03c4\u03b1\u03c2 \u03bc\u03b9\u03b1 \u03b8\u03b5\u03c9\u03c1\u03b7\u03c4\u03b9\u03ba\u03ae \u03b2\u03ac\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03bd\u03ad\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bd\u03c4\u03b9\u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7\u03c2.<\/p>\n<p><b><span>\u0386\u03c4\u03bb\u03b1\u03bd\u03c4\u03b1\u03c2 \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7\u03c2.<\/span><\/b> \u0397 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03c4\u03c9\u03bd \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2. \u03a4\u03b1 \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1 \u03b4\u03b9\u03b1\u03ba\u03c1\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1 (\u03b8\u03cd\u03bc\u03bf\u03c2 \u03b1\u03b4\u03ad\u03bd\u03b1\u03c2, \u03bb\u03b5\u03bc\u03c6\u03b1\u03b4\u03ad\u03bd\u03b5\u03c2, \u03bb\u03b5\u03bc\u03c6\u03bf\u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u0392 \u03ba\u03b1\u03b9 \u03a4, \u03ba\u03bb\u03c0), \u03c3\u03c4\u03b5\u03af\u03c1\u03b1 \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1 (\u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf\u03c2, \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac, \u03bd\u03b5\u03c6\u03c1\u03ac \u03ba\u03b1\u03b9 \u03ae\u03c0\u03b1\u03c1) \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 (\u03b4\u03ad\u03c1\u03bc\u03b1, \u03c0\u03bd\u03b5\u03cd\u03bc\u03bf\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03ad\u03bd\u03c4\u03b5\u03c1\u03bf). \u039f\u03b9 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c6\u03b1\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03cc\u03c1\u03b3\u03b1\u03bd\u03bf<\/p>\n<div><a href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEijYgQUJI42s7yx8oXR-XlvyLS0BnCw9kMyGKkaP3MIouTepQ7-SqW3GDWGPTv07K6GJNcUTfu4yS6t8rdBb2u_kUEIWLiv-wW6IQO0_7xCTBV0GYhIjDa38bYWPNxU90sl2GiW4dIKg0C0Cj548gef0OtPpuT3zeEwhTq-AysrXUsYVsmOZ3jIR0QCBcI\/s1997\/41392_2023_1502_Fig3_HTML.webp\"><img decoding=\"async\" border=\"0\" height=\"624\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEijYgQUJI42s7yx8oXR-XlvyLS0BnCw9kMyGKkaP3MIouTepQ7-SqW3GDWGPTv07K6GJNcUTfu4yS6t8rdBb2u_kUEIWLiv-wW6IQO0_7xCTBV0GYhIjDa38bYWPNxU90sl2GiW4dIKg0C0Cj548gef0OtPpuT3zeEwhTq-AysrXUsYVsmOZ3jIR0QCBcI\/w640-h624\/41392_2023_1502_Fig3_HTML.webp\" width=\"640\" \/><\/a><\/div>\n<p>THE <b>\u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03bd\u03b1\u03ba\u03bf\u03cd\u03c6\u03b9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03b9\u03ce\u03bd \u03c4\u03b7\u03c2 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03b6\u03c9\u03ae\u03c2<\/b> \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 \u03b1\u03c0\u03ce\u03c4\u03b5\u03c1\u03bf\u03b9 \u03c3\u03c4\u03cc\u03c7\u03bf\u03b9 \u03c4\u03b7\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7. \u039f\u03b9 \u03c4\u03c1\u03ad\u03c7\u03bf\u03c5\u03c3\u03b5\u03c2 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bd\u03c4\u03b9\u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03be\u03ac\u03bb\u03b5\u03b9\u03c8\u03b7 \u03c4\u03c9\u03bd \u03b3\u03b7\u03c1\u03b1\u03c3\u03bc\u03ad\u03bd\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd, \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u03b2\u03bb\u03b1\u03c3\u03c4\u03bf\u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03bc\u03cc\u03c3\u03c7\u03b5\u03c5\u03c3\u03b7 \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd, \u03c4\u03c9\u03bd \u03bf\u03c0\u03bf\u03af\u03c9\u03bd \u03b7 \u03bf\u03c5\u03c3\u03af\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03c4\u03b9\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7\u03c2. \u0395\u03c0\u03af\u03c3\u03b7\u03c2 \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03bf\u03bb\u03bf\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c5\u03c0\u03b5\u03c1\u03b8\u03b5\u03c1\u03bc\u03af\u03b1, \u03c4\u03bf\u03bd \u03ba\u03b1\u03b8\u03b1\u03c1\u03b9\u03c3\u03bc\u03cc \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5, \u03c4\u03bf \u03c5\u03c0\u03b5\u03c1\u03b2\u03b1\u03c1\u03b9\u03ba\u03cc \u03bf\u03be\u03c5\u03b3\u03cc\u03bd\u03bf (HBOT), \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 \u03b1\u03c6\u03bf\u03cd \u03b4\u03c1\u03bf\u03c5\u03bd \u03c3\u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2 \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03bf\u03c5\u03bd \u03c3\u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae: \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b5\u03c2, IL-1, IL-6, IL-17, \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03bd\u03ad\u03ba\u03c1\u03c9\u03c3\u03b7\u03c2 \u03cc\u03b3\u03ba\u03bf\u03c5 (TNF), \u03ba\u03bb\u03c0.<\/p>\n<p><\/p>\n<p>*<i> \u03a4\u03bf SASP, \u03c0\u03bf\u03c5 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03bf, \u03b4\u03c5\u03bd\u03b1\u03bc\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd\u03c0\u03bb\u03bf\u03ba\u03bf \u03c6\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03b5\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7. \u0395\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03c6\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf \u03c4\u03c9\u03bd \u03b3\u03b7\u03c1\u03b1\u03c3\u03bc\u03ad\u03bd\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03c0\u03bf\u03c5 \u03b5\u03ba\u03ba\u03c1\u03af\u03bd\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b5\u03c2. 189 \u03a4\u03bf SASP \u03b4\u03b9\u03b1\u03b8\u03ad\u03c4\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03b9\u03c9\u03bd\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 \u03ae \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03c4\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2 \u03b9\u03c3\u03c4\u03bf\u03cd, \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1 \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf \u03c4\u03bf\u03bd \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc. \u039f\u03b9 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03bf\u03af \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 SASP \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b5\u03c2, \u03c7\u03b7\u03bc\u03b5\u03b9\u03bf\u03ba\u03af\u03bd\u03b5\u03c2, \u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2. \u03a4\u03bf SASP \u03b4\u03b9\u03b1\u03b8\u03ad\u03c4\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03b9\u03c9\u03bd\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 \u03ae \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03c4\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2 \u03b9\u03c3\u03c4\u03bf\u03cd, \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1 \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf \u03c4\u03bf\u03bd \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc. \u039f\u03b9 \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03bf\u03af \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 SASP \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03c5\u03c4\u03bf\u03ba\u03af\u03bd\u03b5\u03c2, \u03c7\u03b7\u03bc\u03b5\u03b9\u03bf\u03ba\u03af\u03bd\u03b5\u03c2, \u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2. \u03a3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03ae \u03c4\u03bf\u03c5, \u03c4\u03bf SASP \u03ad\u03c7\u03b5\u03b9 \u03b5\u03bc\u03c0\u03bb\u03b1\u03ba\u03b5\u03af \u03c3\u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03bc\u03b7 \u03b1\u03c5\u03c4\u03cc\u03bd\u03bf\u03bc\u03c9\u03bd \u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b3\u03b7\u03c1\u03b1\u03c3\u03bc\u03ad\u03bd\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2, \u03c4\u03b7\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bf\u03b4\u03b9\u03b1\u03c6\u03c5\u03b3\u03ae\u03c2, \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03ce\u03b8\u03b7\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5, \u03c4\u03b7\u03c2 \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7\u03c2, \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03c1\u03b9\u03bd\u03ae\u03c2 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03cd\u03c4\u03c9 \u03ba\u03b1\u03b8\u03b5\u03be\u03ae\u03c2. \u03a0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03b5\u03bd\u03c4\u03cc\u03c0\u03b9\u03c3\u03b5 \u03ad\u03bd\u03b1 \u03c3\u03cd\u03bd\u03bf\u03bb\u03bf \u03ba\u03bf\u03b9\u03bd\u03ce\u03bd \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bd\u03c4\u03cc\u03c2 \u03c4\u03bf\u03c5 SASP \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b5\u03c0\u03ae \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03b4\u03b9\u03b1\u03c6\u03cc\u03c1\u03c9\u03bd \u03b5\u03c0\u03b1\u03b3\u03c9\u03b3\u03ad\u03c9\u03bd \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c4\u03cd\u03c0\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd. \u0395\u03af\u03bd\u03b1\u03b9 \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03cc\u03c4\u03b9 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ac \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03c0\u03c1\u03c9\u03c4\u03b5\u03ac\u03c3\u03b7\u03c2 \u03c3\u03b5\u03c1\u03af\u03bd\u03b7\u03c2 , stanniocalcin 1 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2&nbsp; C\/EBP\u03b2) \u03ba\u03b1\u03b9 NF-\u03baB, mTOR \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf\u03b9 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 SASP. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03c4\u03bf SASP \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03b5\u03c0\u03b9\u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b1 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03cc\u03c0\u03c9\u03c2 \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7 \u03bb\u03b9\u03c0\u03bf\u03c6\u03bf\u03c5\u03c3\u03ba\u03af\u03bd\u03b7\u03c2 \u03c3\u03c4\u03b1 \u03bb\u03c5\u03c3\u03bf\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1, \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03bf\u03c0\u03bb\u03b1\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc DNA, 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\u03c7\u03c1\u03c9\u03bc\u03b1\u03c4\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03c3\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03c3\u03b7\u03c2 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03b5\u03c3\u03c4\u03b9\u03ce\u03bd \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c4\u03b5\u03bb\u03bf\u03bc\u03b5\u03c1\u03ac\u03c3\u03b7. \u03a3\u03b5 \u03bc\u03b5\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf, \u03bf\u03b9 p16 \u03ba\u03b1\u03b9 p21 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 \u03c0\u03b9\u03bf \u03c3\u03c5\u03c7\u03bd\u03ac \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bc\u03b5\u03bd\u03bf\u03b9 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 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\u03ba\u03b1\u03b9 \u03c3\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2.<\/i><\/p>\n<p><i><br \/><\/i><\/p>\n<p>\u03a0\u03b7\u03b3\u03ae :&nbsp;<span>https:\/\/www.nature.com\/articles\/s41392-023-01502-8<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>&nbsp;\u0397 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7, \u03b1\u03bd\u03bf\u03c3\u03bf\u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7, 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\u03bc\u03b9\u03b1\u2026<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[4580],"class_list":["post-20498","post","type-post","status-publish","format-standard","hentry","category-physiomed","tag-4580"],"_links":{"self":[{"href":"https:\/\/physiomed.store\/en\/wp-json\/wp\/v2\/posts\/20498","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/physiomed.store\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/physiomed.store\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/physiomed.store\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/physiomed.store\/en\/wp-json\/wp\/v2\/comments?post=20498"}],"version-history":[{"count":0,"href":"https:\/\/physiomed.store\/en\/wp-json\/wp\/v2\/posts\/20498\/revisions"}],"wp:attachment":[{"href":"https:\/\/physiomed.store\/en\/wp-json\/wp\/v2\/media?parent=20498"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/physiomed.store\/en\/wp-json\/wp\/v2\/categories?post=20498"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/physiomed.store\/en\/wp-json\/wp\/v2\/tags?post=20498"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}