{"id":20431,"date":"2026-09-19T00:08:00","date_gmt":"2026-09-18T21:08:00","guid":{"rendered":"https:\/\/physiomed.store\/sglt2-%cf%84%ce%bf-%cf%86%ce%ac%cf%81%ce%bc%ce%b1%ce%ba%ce%bf-%cf%84%ce%bf%cf%85-%ce%b4%ce%b9%ce%b1%ce%b2%ce%ae%cf%84%ce%b7-%cf%80%ce%bf%cf%85-%ce%ad%ce%b3%ce%b9%ce%bd%ce%b5-%cf%84%ce%bf-%ce%bd%ce%ad\/"},"modified":"2026-09-19T00:08:00","modified_gmt":"2026-09-18T21:08:00","slug":"sglt2-%cf%84%ce%bf-%cf%86%ce%ac%cf%81%ce%bc%ce%b1%ce%ba%ce%bf-%cf%84%ce%bf%cf%85-%ce%b4%ce%b9%ce%b1%ce%b2%ce%ae%cf%84%ce%b7-%cf%80%ce%bf%cf%85-%ce%ad%ce%b3%ce%b9%ce%bd%ce%b5-%cf%84%ce%bf-%ce%bd%ce%ad","status":"publish","type":"post","link":"https:\/\/physiomed.store\/en\/sglt2-%cf%84%ce%bf-%cf%86%ce%ac%cf%81%ce%bc%ce%b1%ce%ba%ce%bf-%cf%84%ce%bf%cf%85-%ce%b4%ce%b9%ce%b1%ce%b2%ce%ae%cf%84%ce%b7-%cf%80%ce%bf%cf%85-%ce%ad%ce%b3%ce%b9%ce%bd%ce%b5-%cf%84%ce%bf-%ce%bd%ce%ad\/","title":{"rendered":"SGLT2: \u03a4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03c4\u03bf\u03c5 \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7 \u03c0\u03bf\u03c5 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03c4\u03bf \u03bd\u03ad\u03bf \u00ab\u03bc\u03c5\u03c3\u03c4\u03b9\u03ba\u03cc\u00bb \u03c4\u03b7\u03c2 \u03bc\u03b1\u03ba\u03c1\u03bf\u03b6\u03c9\u03af\u03b1\u03c2"},"content":{"rendered":"<div role=\"heading\">\n<p dir=\"ltr\">\n<div><a href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEh4UB98_cHPuyWEgRngVsV-bIQJJvGmdZY2u8QwLcXEvZCRKR9xZZF7M7PDgRXTbQL42Ihx5FaqqUup3q3dBhyphenhyphen6OKbtQU6CV7ihlRfOcJxo4UIurn6GHztsn7yy9oNaRfPdc_OWQ2vWFBfzIsrSqkH1y08wmLearGbgZ-ApNu_cU1Wal9FOIviIXRoqI_w\/s2752\/%CE%91%CE%BD%CE%B1%CF%83%CF%84%CE%BF%CE%BB%CE%B5%CE%AF%CF%82%20SGLT2.jpeg\"><img fetchpriority=\"high\" decoding=\"async\" border=\"0\" height=\"179\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEh4UB98_cHPuyWEgRngVsV-bIQJJvGmdZY2u8QwLcXEvZCRKR9xZZF7M7PDgRXTbQL42Ihx5FaqqUup3q3dBhyphenhyphen6OKbtQU6CV7ihlRfOcJxo4UIurn6GHztsn7yy9oNaRfPdc_OWQ2vWFBfzIsrSqkH1y08wmLearGbgZ-ApNu_cU1Wal9FOIviIXRoqI_w\/s320\/%CE%91%CE%BD%CE%B1%CF%83%CF%84%CE%BF%CE%BB%CE%B5%CE%AF%CF%82%20SGLT2.jpeg\" width=\"320\" \/><\/a><\/div>\n<p>\u03a6\u03b1\u03bd\u03c4\u03b1\u03c3\u03c4\u03b5\u03af\u03c4\u03b5 \u03ad\u03bd\u03b1 \u03c7\u03ac\u03c0\u03b9 \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b5 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03c1\u03c5\u03b8\u03bc\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf \u03b6\u03ac\u03c7\u03b1\u03c1\u03bf, \u03b1\u03bb\u03bb\u03ac \u03c4\u03b5\u03bb\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03b4\u03b5\u03af\u03c7\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u00ab\u03be\u03b5\u03b3\u03b5\u03bb\u03ac\u03c3\u03b5\u03b9\u00bb \u03c4\u03bf \u03c3\u03ce\u03bc\u03b1 \u03bc\u03b1\u03c2, \u03c7\u03b1\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03ac\u03c2 \u03c4\u03bf\u03c5 \u03c4\u03b1 \u03bf\u03c6\u03ad\u03bb\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03ac\u03c3\u03ba\u03b7\u03c3\u03b7\u03c2. \u039f \u03bb\u03cc\u03b3\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 <strong>\u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 SGLT2<\/strong> (\u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03b5\u03bc\u03c0\u03b1\u03b3\u03bb\u03b9\u03c6\u03bb\u03bf\u03b6\u03af\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03b4\u03b1\u03c0\u03b1\u03b3\u03bb\u03b9\u03c6\u03bb\u03bf\u03b6\u03af\u03bd\u03b7), \u03bc\u03b9\u03b1 \u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b1 \u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u0394\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7 \u03a4\u03cd\u03c0\u03bf\u03c5 2 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03be\u03b5\u03c3\u03b7\u03ba\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03bc\u03b5\u03bb\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7.<\/p>\n<p dir=\"ltr\">\u03a0\u03ce\u03c2 \u03cc\u03bc\u03c9\u03c2 \u03ad\u03bd\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03b3\u03b9\u03b1 \u03c4\u03bf \u03b6\u03ac\u03c7\u03b1\u03c1\u03bf \u03ba\u03b1\u03c4\u03b1\u03c6\u03ad\u03c1\u03bd\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03cd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac, \u03c4\u03b1 \u03bd\u03b5\u03c6\u03c1\u03ac \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b2\u03c1\u03b1\u03b4\u03cd\u03bd\u03b5\u03b9 \u03c4\u03bf \u03c1\u03bf\u03bb\u03cc\u03b9 \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5; \u0391\u03c2 \u03c4\u03bf \u03b4\u03bf\u03cd\u03bc\u03b5 \u03bc\u03b5 \u03b1\u03c0\u03bb\u03ac \u03bb\u03cc\u03b3\u03b9\u03b1.<\/p>\n<p><a name=\"more\"><\/a><\/p>\n<p dir=\"ltr\"><\/p>\n<h3 dir=\"ltr\"><span>\u03a4\u03bf \u00ab\u03ba\u03cc\u03bb\u03c0\u03bf\u00bb \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bd\u03b5\u03c6\u03c1\u03bf\u03cd\u03c2: \u03a0\u03ce\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03bf \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 SGLT2;<\/span><\/h3>\n<p dir=\"ltr\">\u039a\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03ac, \u03bf\u03b9 \u03bd\u03b5\u03c6\u03c1\u03bf\u03af \u03bc\u03b1\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03bf\u03cd\u03bd \u03c3\u03b1\u03bd \u03b5\u03be\u03b5\u03bb\u03b9\u03b3\u03bc\u03ad\u03bd\u03b1 \u03c6\u03af\u03bb\u03c4\u03c1\u03b1. \u038c\u03c4\u03b1\u03bd \u03ba\u03b1\u03b8\u03b1\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03bf \u03b1\u03af\u03bc\u03b1, \u03ba\u03c1\u03b1\u03c4\u03ac\u03bd\u03b5 \u03c4\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b1 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c4\u03ac\u03bd\u03b5 \u03c4\u03b1 \u03c3\u03ba\u03bf\u03c5\u03c0\u03af\u03b4\u03b9\u03b1. \u0388\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c0\u03b1\u03b8\u03bf\u03cd\u03bd \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bd\u03b1 \u03ba\u03c1\u03b1\u03c4\u03ae\u03c3\u03bf\u03c5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7 (\u03c4\u03bf \u03b6\u03ac\u03c7\u03b1\u03c1\u03bf), \u03b3\u03b9\u03b1\u03c4\u03af \u03c4\u03b7 \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd \u03c0\u03bf\u03bb\u03cd\u03c4\u03b9\u03bc\u03bf \u03ba\u03b1\u03cd\u03c3\u03b9\u03bc\u03bf.<\/p>\n<p dir=\"ltr\">\u0393\u03b9\u03b1 \u03bd\u03b1 \u03c4\u03bf \u03ba\u03b1\u03c4\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03b1\u03c5\u03c4\u03cc, \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd \u03bc\u03b9\u03b1 \u00ab\u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03b9\u03ba\u03ae \u03c3\u03ba\u03bf\u03cd\u03c0\u03b1\u00bb \u03c0\u03bf\u03c5 \u03bb\u03ad\u03b3\u03b5\u03c4\u03b1\u03b9 <strong>SGLT2<\/strong>. \u0391\u03c5\u03c4\u03cc\u03c2 \u03bf \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03c4\u03bf \u03bd\u03ac\u03c4\u03c1\u03b9\u03bf (\u03c4\u03bf \u03b1\u03bb\u03ac\u03c4\u03b9) \u03c3\u03b1\u03bd \u03ba\u03b1\u03cd\u03c3\u03b9\u03bc\u03bf \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03c1\u03bf\u03c5\u03c6\u03ae\u03be\u03b5\u03b9 \u03c4\u03bf \u03b6\u03ac\u03c7\u03b1\u03c1\u03bf \u03b1\u03c0\u03cc \u03c4\u03b1 \u03bf\u03cd\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c4\u03bf \u03be\u03b1\u03bd\u03b1\u03c1\u03af\u03be\u03b5\u03b9 \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1.<\/p>\n<h4 dir=\"ltr\">\u03a4\u03b9 \u03ba\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf; <span>\u0391\u03c0\u03bb\u03ac \u00ab\u03ba\u03bb\u03b5\u03af\u03bd\u03b5\u03b9\u00bb \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03b9\u03ba\u03ae \u03c3\u03ba\u03bf\u03cd\u03c0\u03b1. \u0388\u03c4\u03c3\u03b9, \u03c4\u03bf \u03c0\u03bb\u03b5\u03cc\u03bd\u03b1\u03c3\u03bc\u03b1 \u03b6\u03b1\u03c7\u03ac\u03c1\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b1\u03bb\u03b1\u03c4\u03b9\u03bf\u03cd \u03b1\u03c0\u03bf\u03b2\u03ac\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ac \u03bc\u03ad\u03c3\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03bf\u03cd\u03c1\u03b1.<\/span><\/h4>\n<p dir=\"ltr\"><strong>\u03a4\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1;<\/strong> \u03a0\u03ad\u03c6\u03c4\u03b5\u03b9 \u03c4\u03bf \u03b6\u03ac\u03c7\u03b1\u03c1\u03bf, \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c0\u03af\u03b5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03be\u03b1\u03bb\u03b1\u03c6\u03c1\u03ce\u03bd\u03b5\u03b9 \u03b7 \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac.<\/p>\n<p dir=\"ltr\"><\/p>\n<h3 dir=\"ltr\"><span>\u039e\u03b5\u03b3\u03b5\u03bb\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf \u03c3\u03ce\u03bc\u03b1: \u0397 \u03c8\u03b5\u03c5\u03b4\u03b1\u03af\u03c3\u03b8\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1\u03c2<\/span><\/h3>\n<p dir=\"ltr\">\u038c\u03c4\u03b1\u03bd \u03b1\u03c0\u03bf\u03b2\u03ac\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5 \u03b6\u03ac\u03c7\u03b1\u03c1\u03bf \u03bc\u03b5 \u03c4\u03b1 \u03bf\u03cd\u03c1\u03b1, \u03c7\u03ac\u03bd\u03bf\u03c5\u03bc\u03b5 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 <strong>200 \u03bc\u03b5 300 \u03b8\u03b5\u03c1\u03bc\u03af\u03b4\u03b5\u03c2 \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1<\/strong> \u03c7\u03c9\u03c1\u03af\u03c2 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03bf\u03c5\u03bc\u03b5 \u03b4\u03af\u03b1\u03b9\u03c4\u03b1. \u03a4\u03bf \u03c3\u03ce\u03bc\u03b1 \u03bc\u03b1\u03c2 \u03bc\u03c0\u03b5\u03c1\u03b4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03bd\u03bf\u03bc\u03af\u03b6\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03bb\u03b9\u03bc\u03bf\u03ba\u03c4\u03bf\u03bd\u03b5\u03af!<\/p>\n<p dir=\"ltr\">\u0393\u03b9\u03b1 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b9\u03ce\u03c3\u03b5\u03b9, \u03b3\u03c5\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf\u03bd \u03b4\u03b9\u03b1\u03ba\u03cc\u03c0\u03c4\u03b7: \u03c3\u03c4\u03b1\u03bc\u03b1\u03c4\u03ac \u03bd\u03b1 \u03ba\u03b1\u03af\u03b5\u03b9 \u03c5\u03b4\u03b1\u03c4\u03ac\u03bd\u03b8\u03c1\u03b1\u03ba\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c1\u03c7\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03ba\u03b1\u03af\u03b5\u03b9 \u03c4\u03bf \u03b1\u03c0\u03bf\u03b8\u03b7\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf \u03bb\u03af\u03c0\u03bf\u03c2. \u0391\u03c5\u03c4\u03ae \u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03b9 <strong>\u03ba\u03b5\u03c4\u03cc\u03bd\u03b5\u03c2<\/strong>, \u03ad\u03bd\u03b1 \u03c5\u03c0\u03b5\u03c1-\u03ba\u03b1\u03cd\u03c3\u03b9\u03bc\u03bf \u03c0\u03bf\u03c5 \u03bb\u03b1\u03c4\u03c1\u03b5\u03cd\u03bf\u03c5\u03bd \u03b7 \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac \u03ba\u03b1\u03b9 \u03bf \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf\u03c2, \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03ac\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1 \u03bc\u03b5 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03b7 \u00ab\u03c1\u03cd\u03c0\u03b1\u03bd\u03c3\u03b7\u00bb (\u03bf\u03be\u03b5\u03b9\u03b4\u03c9\u03c4\u03b9\u03ba\u03cc \u03c3\u03c4\u03c1\u03b5\u03c2).<\/p>\n<p dir=\"ltr\"><\/p>\n<h3 dir=\"ltr\"><span>\u039f\u03b9 3 \u00ab\u0394\u03b9\u03b1\u03ba\u03cc\u03c0\u03c4\u03b5\u03c2\u00bb \u03c4\u03b7\u03c2 \u039c\u03b1\u03ba\u03c1\u03bf\u03b6\u03c9\u03af\u03b1\u03c2: SIRT1, AMPK \u03ba\u03b1\u03b9 mTOR<\/span><\/h3>\n<p dir=\"ltr\">\u03a4\u03bf \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03b8\u03b1\u03cd\u03bc\u03b1 \u03cc\u03bc\u03c9\u03c2 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03ac \u03bc\u03b1\u03c2. \u0391\u03c5\u03c4\u03ae \u03b7 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u00ab\u03c8\u03b5\u03c5\u03b4\u03bf-\u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1\u03c2\u00bb \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03c4\u03bf\u03c5\u03c2 \u03c4\u03c1\u03b5\u03b9\u03c2 \u03c0\u03b9\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5\u03bd \u03c4\u03b7 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7:<\/p>\n<ul dir=\"ltr\">\n<li><strong>AMPK (\u0397 \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7 \u00ab\u03a7\u03b1\u03bc\u03b7\u03bb\u03ae \u039c\u03c0\u03b1\u03c4\u03b1\u03c1\u03af\u03b1\u00bb):<\/strong> \u0395\u03af\u03bd\u03b1\u03b9 \u03bf \u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03ae\u03c1\u03b1\u03c2 \u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03bf\u03c5. \u038c\u03c4\u03b1\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9, \u03b4\u03af\u03bd\u03b5\u03b9 \u03b5\u03bd\u03c4\u03bf\u03bb\u03ae \u03c3\u03c4\u03bf \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03bf \u03bd\u03b1 \u03c3\u03c4\u03b1\u03bc\u03b1\u03c4\u03ae\u03c3\u03b5\u03b9 \u03bd\u03b1 \u03be\u03bf\u03b4\u03b5\u03cd\u03b5\u03b9 \u03ac\u03c3\u03ba\u03bf\u03c0\u03b1 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03be\u03b5\u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 <em>\u03b1\u03c5\u03c4\u03bf\u03c6\u03b1\u03b3\u03af\u03b1\u03c2<\/em> \u2013 \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03bd\u03b1 \u03b1\u03bd\u03b1\u03ba\u03c5\u03ba\u03bb\u03ce\u03c3\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03ba\u03b1\u03b8\u03b1\u03c1\u03af\u03c3\u03b5\u03b9 \u03c4\u03b1 \u03c7\u03b1\u03bb\u03b1\u03c3\u03bc\u03ad\u03bd\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03be\u03b1\u03c1\u03c4\u03ae\u03bc\u03b1\u03c4\u03b1 (\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ac \u03c3\u03ba\u03bf\u03c5\u03c0\u03af\u03b4\u03b9\u03b1).<\/li>\n<li><strong>SIRT1 (\u039f \u0395\u03c0\u03b9\u03b8\u03b5\u03c9\u03c1\u03b7\u03c4\u03ae\u03c2 \u03a0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2):<\/strong> \u0395\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c0\u03b5\u03c1\u03af\u03c6\u03b7\u03bc\u03b1 \u00ab\u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03b1 \u03bc\u03b1\u03ba\u03c1\u03bf\u03b6\u03c9\u03af\u03b1\u03c2\u00bb. \u038c\u03c4\u03b1\u03bd \u03c0\u03b1\u03af\u03c1\u03bd\u03b5\u03b9 \u03bc\u03c0\u03c1\u03bf\u03c2, \u03b4\u03b9\u03bf\u03c1\u03b8\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03b2\u03bb\u03ac\u03b2\u03b5\u03c2 \u03c3\u03c4\u03bf DNA \u03bc\u03b1\u03c2, \u03c3\u03b2\u03ae\u03bd\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b5\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c6\u03c4\u03b9\u03ac\u03c7\u03bd\u03b5\u03b9 \u03bd\u03ad\u03b1, \u03bf\u03bb\u03bf\u03ba\u03b1\u03af\u03bd\u03bf\u03c5\u03c1\u03b3\u03b9\u03b1 \u00ab\u03b5\u03c1\u03b3\u03bf\u03c3\u03c4\u03ac\u03c3\u03b9\u03b1 \u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1\u03c2\u00bb (\u03bc\u03b9\u03c4\u03bf\u03c7\u03cc\u03bd\u03b4\u03c1\u03b9\u03b1) \u03c3\u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1.<\/li>\n<li><strong>mTOR (\u039f \u03b4\u03b9\u03b1\u03ba\u03cc\u03c0\u03c4\u03b7\u03c2 \u03c4\u03b7\u03c2 \u0391\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2):<\/strong> \u0391\u03c5\u03c4\u03cc\u03c2 \u03bf \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03c4\u03c1\u03ce\u03bc\u03b5 \u03c0\u03bf\u03bb\u03cd \u03ba\u03b1\u03b9 \u03bb\u03ad\u03b5\u03b9 \u03c3\u03c4\u03bf \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03bf \u03bd\u03b1 \u03bc\u03b5\u03b3\u03b1\u03bb\u03ce\u03c3\u03b5\u03b9. \u038c\u03bc\u03c9\u03c2, \u03b7 \u03c3\u03c5\u03bd\u03b5\u03c7\u03ae\u03c2 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c6\u03ad\u03c1\u03bd\u03b5\u03b9 \u03c0\u03c1\u03cc\u03c9\u03c1\u03b7 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7. \u03a4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf SGLT2 \u03c0\u03b1\u03c4\u03ac\u03b5\u03b9 \u03c6\u03c1\u03ad\u03bd\u03bf \u03c3\u03c4\u03bf mTOR, \u03b4\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c3\u03c4\u03bf \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03bf \u03c4\u03bf\u03bd \u03c7\u03c1\u03cc\u03bd\u03bf \u03bd\u03b1 \u03be\u03b5\u03ba\u03bf\u03c5\u03c1\u03b1\u03c3\u03c4\u03b5\u03af, \u03bd\u03b1 \u03b1\u03c5\u03c4\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b5\u03af \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b6\u03ae\u03c3\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf.<\/li>\n<\/ul>\n<h3 dir=\"ltr\">\u039c\u03b5 \u03bb\u03af\u03b3\u03b1 \u03bb\u03cc\u03b3\u03b9\u03b1<\/h3>\n<p dir=\"ltr\">\u039f\u03b9 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 SGLT2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bb\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7. \u0395\u03af\u03bd\u03b1\u03b9 <strong>\u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03ad\u03c2 \u03c4\u03b7\u03c2 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bc\u03b1\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2<\/strong>. \u0394\u03b9\u03ce\u03c7\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03c4\u03c4\u03cc \u03b6\u03ac\u03c7\u03b1\u03c1\u03bf \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b1\u03bb\u03ac\u03c4\u03b9, \u03b1\u03bd\u03b1\u03b3\u03ba\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03bf \u03c3\u03ce\u03bc\u03b1 \u03bd\u03b1 \u03bc\u03c0\u03b5\u03b9 \u03c3\u03b5 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03b1\u03c5\u03c4\u03bf\u03c3\u03c5\u03bd\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b9\u03b4\u03b9\u03cc\u03c1\u03b8\u03c9\u03c3\u03b7\u03c2 \u2013 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ce\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03bc\u03b5 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03bb\u03b5\u03b9\u03bc\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03ad\u03bd\u03c4\u03bf\u03bd\u03b7 \u03b3\u03c5\u03bc\u03bd\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae.<\/p>\n<p dir=\"ltr\"><\/p>\n<blockquote>\n<p dir=\"ltr\"><strong>\u03a3\u03b7\u03bc\u03b5\u03af\u03c9\u03c3\u03b7:<\/strong> <i>\u0391\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03bd\u03c4\u03c5\u03c0\u03c9\u03c3\u03b9\u03b1\u03ba\u03ac, \u03c4\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03b1\u03c5\u03c4\u03ac \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ac \u03c3\u03ba\u03b5\u03c5\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2 (\u03cc\u03c0\u03c9\u03c2 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